We at Janini IVF would like to introduce a breakthrough in our already excellent treatment protocols and success rates by incorporating a totally new method firstly introduced in the country called “Robotic ICSI”. In this procedure instead of the sperm being manually picked by the senior embryologist and immobilised for fertilisation of the egg used during conventional ICSI, there are small robots or “nanobots” used that pick up the tail of the best sperm chosen and then artificially inject them.into the eggs leading to successful fertilisation.
Since its invention 20 years ago, conventional ICSI has been found to have numerous
disadvantages namely manually being dependent on the embryologist, clinical errors in selection
of the sperm, nuances while performing the procedure, etc. Robotic ICSI has the advantages of
being standardised, less clinically dependent (require only a few mouse clicks), has been shown
to have consistent results and results in a high degree of reproducibility. The system requires
hardly any human intervention and is operator skill independent. Using the robotic ICSI gave the
original researchers over 96% fertilisation rate, 67% blastulation rate and 75% clinical pregnancy
rate in one cohort of patients comprising 156 couples (both self and donor eggs).
We, truly at Janini IVF, have developed a unique cell manipulation technology by introducing a
vacuum based cell holding device for immobilising many oocytes, eliminating the need of random
cell search. For sperm manipulation, we use a visual tracking algorithm achieving more than 95%
success rates consistently over a diverse subgroup of population. The robotic ICSI system
demonstrates a high degree of reproducibility and operator skill independence. Clinical trials are
already underway in different parts of the world. Although not started for clinical patients, we are
underway to develop this first time in the country.
